Colon Cancer – Medical Cannabis Research

Colon cancer is cancer of the large intestine (colon), the lower part of your digestive system. Rectal cancer is cancer of the last several inches of the colon. Together, they’re often referred to as colorectal cancers.

Recent years have brought a wealth of new scientific understanding regarding how medical marijuana or cannabis can be beneficial for treating Colon Cancer.

Most cases of colon cancer begin as small, noncancerous (benign) clumps of cells called adenomatous polyps. Over time some of these polyps become colon cancers.

Polyps may be small and produce few, if any, symptoms. For this reason, doctors recommend regular screening tests to help prevent colon cancer by identifying polyps before they become colon cancer.

Clinical Research on Colon Cancer and Medical Marijuana Cannabis

• Chemopreventive effect of the non-psychotropic phytocannabinoid cannabidiol on experimental colon cancer
• Cannabinoids in intestinal inflammation and cancer
• The cannabinoid delta(9)-tetrahydrocannabinol inhibits RAS-MAPK and PI3K-AKT survival signalling and induces BAD-mediated apoptosis in colorectal cancer cells
• Turned-off Cannabinoid Receptor Turns on Colorectal Tumor Growth
• Colon carcinogenesis is inhibited by the TRPM8 antagonist cannabigerol, a Cannabis-derived non-psychotropic cannabinoid
• The endogenous cannabinoid, anandamide, induces cell death in colorectal carcinoma cells: a possible role for cyclooxygenase 2